Clinical Research Directory
Browse clinical research sites, groups, and studies.
Bronchial Thermoplasty for Severe Asthma With Dynamic Hyperinflation
Sponsor: University Hospital, Toulouse
Summary
Bronchial thermoplasty is a treatment for severe asthma that consist in decreasing the thickness of bronchial muscle by heat using a catheter inserted into the bronchi under direct vision with the help of an endoscope This treatment has shown efficacy on symptoms, quality of life and the number of exacerbations related to severe asthma. This clinical study evaluates the efficiency of this treatment on the dynamic hyperinflation phenomenon (worsening of bronchial obstruction during exercise in patients with asthma contributing to worsening shortness of breath).
Official title: Evaluation of the Efficiency of Bronchial Thermoplasty on Dynamic Hyperinflation in Uncontrolled Severe Asthma
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
14
Start Date
2015-11
Completion Date
2021-05-06
Last Updated
2026-05-29
Healthy Volunteers
No
Conditions
Interventions
Bronchial thermoplasty for treatment of severe asthma
Three sessions of bronchial thermoplasty are needed to treat patients. There will be 3 to 4 weeks between each procedure. Bronchial thermoplasty procedure is performed under general anesthesia. The medical device used in this research to achieve the thermoplasty is the Alair system (class IIb medical device ; Boston scientific) A confocal endomicroscopy will be conducted at the first and final session of thermoplasty. This examination involves analyzing and recording the structure of bronchi microscopy through a small catheter placed on the bronchus. Photographs of the bronchi will be realized.
Locations (1)
DIDIER Alain
Toulouse, Midi Pyrenees, France