Clinical Research Directory

Inclusion Criteria: 1. Subjects must be either currently enrolled in the OPPORTUNITY trial (NCT02602457) or have paroxysmal atrial fibrillation and be scheduled to undergo catheter ablation (for the first time) through the electrophysiology clinic at the University of Ottawa Heart Institute. 2. Subjects must be willing and able to provide a blood sample. 3. Subjects must be willing and able to provide informed consent. Exclusion Criteria: 1. Subject is not either currently enrolled in the OPPORTUNITY trial (NCT02602457) or scheduled to undergo catheter ablation (for the first time) through the electrophysiology clinic at the University of Ottawa Heart Institute for paroxysmal atrial fibrillation. 2. Subjects with congestive heart failure with heart failure admission in the past 3 months. 3. Subjects with a cerebrovascular accident in the past 3 months 4. Subjects with severe dementia. 5. Subjects with a history of severe psychiatric illness (e.g., schizoaffective disorder, bipolar disorder, or schizophrenia). 6. Subjects with an active infection or inflammatory condition. 7. Subjects who are pregnant, lactating or planning to become pregnant during the study period. 8. Subject is unable to read or understand English or French. 9. Subject is unable to provide informed consent.