Clinical Research Directory

Inclusion Criteria: * Patients included between 20-70 years * ASA 1-4 * Euroscore value lower than 7 * Undergoned non coronary heart surgery (minithoracotomy) * Intensive care has been discharged from the service in 24 hours , with patients given tramadol retard , metamizol, Dexketoprofen on postoperatif first day to discharged from the hospital. Exclusion Criteria: * Diabetes mellitus * Chronic renal failure * COPD * Uncontrolled hypertension * Epilepsy * Psychiatric disease * Malignancy * Patients with a history of cerebrovascular disease * Patients with ischemia * Patients suffering from chronic pain and analgesic use * Patients taking antidepressants and antiepileptic drug * Off-pump technique used or redo undergo cases * Ongoing postoperative time thoracic or mediastinal drains more than 48 hours remaining patients, bleeding or patients who received repeated revisions due to infection * More than 24 hours remaining in intensive care patients * Patients with long discharge duration 1 week * Patients who discontinued due to side effects of tramadol may begin after medicines. * Postoperative wound infection.