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Esophageal Manometry During Recovery From Anesthesia: Pilot Study
Sponsor: University of California, San Francisco
Summary
1. An intact pharyngoesophageal reflex is essential to protect the upper airway from aspiration of either mouth contents or regurgitated gastric refluxate. This reflex is essential at protecting the airway in all patients. 2. In patients, while under general anesthesia, it is postulated that an identifiable upper esophageal sphincter and esophageal peristalsis are not present. 3. With the cessation of general anesthetics, accompanied by the reversal of nerve block, normal pharyngoesophageal peristaltic activity correlates with awakening the patient from anesthesia. This would be identified by the performance of esophageal manometry. 4. A return of normal verbally stimulated pharyngoesophageal swallowing sequence accurately identifies a safe time to remove endotracheal tubes and/or reverse anesthesia. This verbally stimulated swallowing sequence correlated precisely with the return of objective pharyngoesophageal function.
Key Details
Gender
All
Age Range
18 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
32
Start Date
2016-01
Completion Date
2019-03-05
Last Updated
2026-08-20
Healthy Volunteers
No
Conditions
Interventions
Motility Procedure
The use of esophageal manometry device during general anesthesia
Locations (1)
Zuckerberg San Francisco General Hospital
San Francisco, California, United States