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Cough, Expiratory Training, and Chronic Aspiration After Head and Neck Radiotherapy
Sponsor: M.D. Anderson Cancer Center
Summary
The goal of this clinical research study is to learn if exercising the muscles that help you cough and swallow, called expiratory muscle strength training (EMST), can help reduce the risk of pneumonia due to aspiration (inhaling saliva instead of swallowing it) in patients who have had radiation for head and neck cancer.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
175
Start Date
2016-02-01
Completion Date
2027-02-02
Last Updated
2025-10-27
Healthy Volunteers
No
Conditions
Interventions
Barium Swallow
Participants receive modified barium swallow at baseline and after 8 weeks of using the EMST device
Questionnaires
Questionnaires completed about symptoms and quality of life at baseline, after 8 weeks of using the EMST device, and 12 months after completing the study.
Expiratory Muscle Strength Training (EMST) Device
Participant uses the EMST device at home on a 5-5-5 schedule (5 repetitions, 5 sets, 5 days per week) for 8 weeks.
Digital Manometer
Digital manometer used to test how forcefully participant is able to exhale and cough at baseline, and one time each week for 8 weeks while using the EMST device.
Neurocognitive Exams
Participants given neurocognitive exams at baseline.
Barium
Participants receive barium prior to modified barium swallow at baseline and after 8 weeks of using the EMST device.
Locations (1)
University of Texas MD Anderson Cancer Center
Houston, Texas, United States