Clinical Research Directory

Inclusion Criteria: * Patients being evaluated for Alzheimer disease and related dementias according to the HAS recommendations (atypical dementia, early onset and rapid progressive dementia) * Patients who have previously been evaluated for AD and related dementias to whom a CSF examination was recommended in the last 12 months, but lumbar puncture was contraindicated or refused or CSF results were ambiguous, or * Patients currently being evaluated for AD and related dementias to whom a CSF examination is recommended but lumbar puncture is contraindicated or refused * Patients have a study partner who is willing and able to accompany him/her to all clinic visits for the duration of the protocol * Patients able to complete all clinical visits according to the protocol * Patients able to tolerate a 20-minute FBB PET scan * Patient or legal representative to provide informed consent for study participation, visits and data source verification. Exclusion Criteria: * The subject had a previous beta amyloid imaging scan * Any significant systemic illness or unstable medical condition which could lead to difficulty complying with the protocol * Is currently receiving any investigational pharmaceutical product or has participated in a clinical trial with an investigational pharmaceutical product within 30 days prior to screening and/or was administered a radiopharmaceutical within 10 radioactive half-lives prior to study drug administration in this study * For females of childbearing age, a positive pregnancy test