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Randomized Trial Comparing Performance of Molecular Markers for Indeterminate Thyroid Nodules
Sponsor: Jonsson Comprehensive Cancer Center
Summary
The purpose of this study is to compare the performance of Afirma GSC and ThyroSeq v.3 in indeterminate thyroid nodules to determine which test can allow more patients to avoid unnecessary surgery and preserve quality of life. In the initial phase of this study, the performance of Afirma GEC and ThyroSeq v.2 were compared.
Key Details
Gender
All
Age Range
18 Years - 100 Years
Study Type
OBSERVATIONAL
Enrollment
328
Start Date
2016-05-01
Completion Date
2027-12-01
Last Updated
2025-12-22
Healthy Volunteers
No
Conditions
Interventions
Afirma GEC
Afirma GEC molecular test on collected thyroid tissue
ThyroSeq v.2
ThyroSeq v.2 molecular test on collected thyroid tissue
Afirma GSC
Afirma GSC molecular test on collected thyroid tissue
ThyroSeq v.3
ThyroSeq v.3 molecular test on collected thyroid tissue
Locations (1)
Jonsson Comprehensive Cancer Center at UCLA
Los Angeles, California, United States