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ACTIVE NOT RECRUITING
NCT02701699
NA

18F-Fluoroazomycin Arabinoside (18F-FAZA) in Lung Cancer

Sponsor: University Health Network, Toronto

View on ClinicalTrials.gov

Summary

The purpose of this study is to look for low levels of oxygen (hypoxia) in lung cancer using a positron emission tomography (PET) scan. Hypoxia can influence how lung cancer grows and responds to treatments like radiotherapy and chemotherapy. The use of PET scans to measure hypoxia may be better and simpler than the approaches used previously. This study will assess whether or not PET scans can provide useful information about hypoxia in lung cancer. In this study, a radiotracer called Fluoroazomycin Arabinoside (FAZA) will be used to measure hypoxia in the patient's tumour. FAZA has already been used in many cancers including lung cancer. Patients who consent to participate in this trial will receive 1 FAZA PET Scan prior to their first radiotherapy treatment

Official title: A Feasibility Study of Hypoxia Imaging in Patients With Lung Cancer Using Positron Emission Tomography (PET) With 18F-Fluoroazomycin Arabinoside (18F-FAZA)

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

36

Start Date

2014-12

Completion Date

2027-06

Last Updated

2026-03-06

Healthy Volunteers

No

Conditions

Interventions

BIOLOGICAL

18-F-FAZA

All patients enrolled in this study will receive a FAZA PET Scan prior to their first radiation therapy fraction

Locations (1)

University Health Network, Princess Margaret Cancer Centre

Toronto, Ontario, Canada