Clinical Research Directory
Browse clinical research sites, groups, and studies.
Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study I
Sponsor: Yale University
Summary
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
Key Details
Gender
All
Age Range
21 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2016-03
Completion Date
2025-12
Last Updated
2025-04-15
Healthy Volunteers
Yes
Interventions
Active inhaled delta-9-THC
Low dose THC (\~4 mg), dissolved in alcohol. This dose is roughly equivalent to smoking approximately 1/4 of a marijuana cigarette, or "joint". Administered over 20 minutes via a vaporizer.
Placebo
Control: Approximately 4 drinks of orange juice or ginger ale covered by a trace amount of ethanol on the surface, each administered over approximately 10 minutes.
Placebo
Control: No active THC. Administered over 20 minutes via a vaporizer. approximately 10 minutes.
Active Oral Ethanol
0.4 g/kg ethanol in orange juice or ginger ale to reach a target BrAC of approximately 0.04%. This dose is equivalent to consuming approximately 2 standard drinks over 1 hour. Approximately 4 drinks, each administered over approximately 10 minutes.
Locations (1)
Biological Studies Unit, VA Connecticut Healthcare System
West Haven, Connecticut, United States