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Ethanol and Cannabinoid Effects on Simulated Driving and Related Cognition: Sub-Study II
Sponsor: Yale University
Summary
The overarching goal of this study is to characterize the effects of ethanol and cannabinoids on simulated driving and related cognition.
Key Details
Gender
All
Age Range
21 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2016-03
Completion Date
2025-12
Last Updated
2025-04-15
Healthy Volunteers
Yes
Interventions
Active inhaled cannabis
\~450 mg of active cannabis, which is roughly equivalent to smoking 1/4 of a marijuana cigarette, or "joint". Administered over 20 minutes via a vaporizer.
Placebo
Approximately 4 drinks of orange juice or ginger ale covered with a trace amount of ethanol on the surface, each administered over approximately 10 minutes.
Active Oral Ethanol
0.4 g/kg ethanol in orange juice or ginger ale to reach a target BrAC of approximately 0.04%. This dose is equivalent to approximately 2 standard drinks over 1 hour. Approximately 4 drinks, each administered over approximately 10 minutes.
Placebo
No active cannabinoids. Administered over 20 minutes via a vaporizer.
Locations (1)
Biological Studies Unit, VA Connecticut Healthcare System
West Haven, Connecticut, United States