Clinical Research Directory

Inclusion Criteria * 8 - 21 years old * Diagnosis of Cystic Fibrosis confirmed by genetic studies and/or sweat chloride testing * Baseline pulmonary function testing (PFT) (within the last 3 months) with FEV1 (Forced expiratory volume in 1 second) \> 40% * Must be able to perform 3-minute step test. * Must achieve an adequate 15 count breathlessness score. Must be able to perform ergometry testing utilizing extremities * Must have a working computer/smartphone/tablet with internet connection at home Exclusion criteria * FEV1 \< 40% * Desaturations (less than 75%) or significant fatigue with 3-minute step test 15 count breathlessness score of greater than 2 * Pulmonary exacerbation (shortness of breath or difficulty breathing requiring hospitalization) within the last 4 weeks * Oxygen requirement at rest or during sleeping. * Recent pneumothorax (popped lung) within last 3 months * Moderate pulmonary hypertension (increased pressure in the lung arteries) diagnosed via echocardiogram. * History of low ejection fraction (percentage of blood being pumped out of the heart) via echocardiogram. * History of cardiac ischemia (reduced blood supply to heart tissue). * Uncontrolled systemic hypertension for patient age and height. * Moderate to severe scoliosis (abnormal curvature of the spine)