Clinical Research Directory

Inclusion Criteria: * Patient 30 to 80 years * Parkinson's disease according to the criteria of the United Kingdom Parkinson's Disease Society Brain Bank * Presence of constipation defined by the Rome III criteria Functional constipation * Social assured Patient * Patients with signed consent Exclusion Criteria: * Organic Affection colic * Constipation Drug * Other neurological disorder Parkinson's disease * Metabolic disease diabetes collagenoses * Severe renal or hepatic impairment * Pregnant or lactating women * Premenopausal women without contraceptive device effective * Regular and prolonged use of history (\> 12 months) of laxatives irritants * Use of oral laxative treatment in the two weeks before the start of treatment, and refusal to stop these treatment during the course of the study * Taking treatment antabuse * Cognitive impairment compromising understanding or application instructions * Patient already included in a research protocol * Minors * Nobody protected by law