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Modifications of the Subchondral Bone in Aseptic Osteonecrosis of the Femoral Head
Sponsor: Lille Catholic University
Summary
In this study, the aim is to identify the modifications responsible for aseptic osteonecrosis of the femoral head and its structural evolution by the association of the micro scanner analysis and Raman spectrometry performed on the femoral heads removed during hip replacements. The study of femoral heads will allow the analysis of bone tissue at two different scales, both correlated with the biomechanical properties of the bone. Also, the association with preliminary MRI analysis will provide pathogenic explanations correlated to these modifications.
Official title: Study of Modifications of the Composition and Structure in the Aseptic Osteonecrosis of the Femoral Head and Etiopathogenic MRI Correlations
Key Details
Gender
MALE
Age Range
25 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
34
Start Date
2016-02
Completion Date
2020-12
Last Updated
2026-04-17
Healthy Volunteers
No
Conditions
Interventions
femoral head removal
Locations (2)
Hospital Salengro CHU Lille
Lille, France
Hospital Group of the Catholic Institute of Lille
Lomme, France