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ACTIVE NOT RECRUITING
NCT02735083
PHASE1

A Study to Evaluate the Long-term Safety of Patients With Advanced Lymphoid Leukemia Who Have Been Previously Administered With UCART19

Sponsor: Institut de Recherches Internationales Servier

View on ClinicalTrials.gov

Summary

The purpose of this study is to evaluate the long-term safety and efficacy of UCART19 administration to patients with advanced lymphoid leukemia.

Official title: Long-term Follow-up Study of Patients Who Have Previously Been Exposed to UCART19 (Allogeneic Engineered T-cells Expressing a Lentiviral-based Anti-CD19 Chimeric Antigen Receptor)

Key Details

Gender

All

Age Range

Any - Any

Study Type

INTERVENTIONAL

Enrollment

28

Start Date

2021-03-10

Completion Date

2028-09

Last Updated

2025-04-11

Healthy Volunteers

No

Interventions

BIOLOGICAL

UCART19 follow-up

UCART19 will not be administered during the study period. Patients who will be rolled-over from the parent study to this long term follow-up study, have previously received UCART19. The roll-over occurs at the end of the parent study, or at any time after UCART19 administration, in case of premature discontinuation from the parent study.

Locations (16)

Children's Hospital Los Angeles

Los Angeles, California, United States

Colorado Blood Cancer Institute

Denver, Colorado, United States

Moffit Cancer Center

Tampa, Florida, United States

Massachussetts General Hospital

Charlestown, Massachusetts, United States

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States

University of Texas Southwestern Medical Center

Dallas, Texas, United States

University of Texas MD Anderson Cancer Center

Houston, Texas, United States

Hôpital Saint-Louis

Paris, France

Hôpital Robert-Debré

Paris, France

Hôpital Saint-Antoine

Paris, France

Kyushyu University Hospital

Fukuoka, Japan

Hokkaido University Hospital

Sapporo, Japan

Hospital San Juan De Dios

Barcelona, Spain

King's College Hospital NHS Foundation Trust

London, United Kingdom

UCL Great Ormond Hospital

London, United Kingdom

The Christie NHS Foundation Trust

Manchester, United Kingdom