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DCE-MRI and MBI in Assessing Tumor Response to Chemotherapy in Patients With Triple Negative Breast Cancer
Sponsor: M.D. Anderson Cancer Center
Summary
This early phase I trial studies how well dynamic contrast enhanced molecular resonance imaging (DCE-MRI) and technetium-Tc99m sestamibi molecular breast imaging (MBI) work in assessing tumor response to chemotherapy in patients with triple negative breast cancer (TNBC) who are undergoing chemotherapy. Investigational imaging scans such as MBI and DCE-MRI may help researchers predict which patients may respond to treatment.
Official title: Multimodality Breast Imaging for the Assessment of Tumor Response to Neoadjuvant Chemotherapy in Triple Negative Breast Cancer Patients
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
96
Start Date
2016-11-07
Completion Date
2026-04-30
Last Updated
2025-10-20
Healthy Volunteers
No
Conditions
Interventions
Dynamic Contrast-Enhanced Magnetic Resonance Imaging
Undergo DCE-MRI
Laboratory Biomarker Analysis
Correlative studies
Scintimammography
Undergo MBI
Technetium Tc-99m Sestamibi
Given via injection
Locations (6)
Memorial Hermann Memorial City Medical Center
Houston, Texas, United States
M D Anderson Cancer Center
Houston, Texas, United States
MD Anderson in Katy
Houston, Texas, United States
MD Anderson League City
Nassau Bay, Texas, United States
MD Anderson in Sugar Land
Sugar Land, Texas, United States
MD Anderson in The Woodlands
The Woodlands, Texas, United States