Clinical Research Directory

Inclusion Criteria: * Patients ≥18 years old scheduled for elective thoracic surgery (segmentectomy, lobectomy or bi-lobectomy, pneumonectomy or esophagectomy) and meeting one of the four following risk criteria: * 1\. Female \& BNP ≥ 25pg/ml (no age limit) * 2\. Male gender \<75 \& BNP ≥ 25pg/ml * 3\. Male- age ≥75 (No BNP limit) * 4\. History of prior AF * Patients in sinus rhythm. * Patients with stable respiratory status (no respiratory distress). * Patients capable of providing written, informed consent. Exclusion Criteria: * Patients scheduled for extrapleural pneumonectomy. * Hemodynamically unstable patients (not in cardiogenic shock or having an acute MI). * Patients with 2nd or 3rd degree atrioventricular (AV) block. * Patients with hypersensitivity to amiodarone or NAC. * Patients already taking class Ic or III antiarrhythmic drugs. * Hepatic insufficiency (≤2 times the upper normal limit of transaminase levels). * Renal insufficiency (creatinine ≥2.0 mg/dl). * Known pregnancy.