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Effect of Irradiation of the Cavernous Sinus and the Sellar Region on Autobiographical Memory
Sponsor: University Hospital, Bordeaux
Summary
Several studies showed that radiotherapy as brain tumors treatment may affect cognition. It was observed that durable memory impairments could arise at irradiated patients if radiotherapy is applied on medial temporal lobes. However, results concerned studies of anterograde memory and none, this day, estimates the impact of radiotherapy on autobiographical memory which also involves hippocampus. The aim of this study is to evaluate effects of cavernous sinus or sellar region irradiation on autobiographical memory. Thirty 35 to 65 years old patients, with cavernous sinus meningioma or pituitary adenoma for who radiotherapy is indicated will be recruited.
Key Details
Gender
All
Age Range
35 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
17
Start Date
2016-07-27
Completion Date
2022-03
Last Updated
2026-05-14
Healthy Volunteers
No
Interventions
Evaluation of autobiographical memory
Patients will answer several questionnaires one and two years after irradiation treatment end.
Locations (1)
University Hospital Bordeaux
Bordeaux, France