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COMPLETED
NCT02765529
NA

Biomarkers of Exposure to Air Pollutants (AEROTOX-2)

Sponsor: Lille Catholic University

View on ClinicalTrials.gov

Summary

Nowadays, an increase of inflammatory chronic diseases and/or tumors incidence has been reported in part due to the rising in life expectancy. For instance, exposure to air pollution, and in particularly to fine particles has been classified by the International Agency for Research on Cancer (IARC) as a risk factor for cancer, being the elderly population particularly sensitive. However, no validated biomarkers have been identified to assess the exposure to fine particles maybe correlated to cancerogenesis. AEROTOX-2 is a prospective pilot study on the ex vivo effects of the atmospheric pollution exposure. The study aims to identity new biomarkers after an exposure of leukocytes to doses of fine particles. Secondly, the study aims to analyze, according to age, the leukocytes response to the urban pollution exposure.

Official title: Research of Biomarkers of Air Pollutants Exposure

Key Details

Gender

All

Age Range

20 Years - 80 Years

Study Type

INTERVENTIONAL

Enrollment

101

Start Date

2015-11

Completion Date

2016-12

Last Updated

2026-04-20

Healthy Volunteers

Yes

Interventions

PROCEDURE

Blood sampling

Locations (1)

Clinical Nutrition Center Naturalpha

Lille, Hauts-de-France, France