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Physiologic Assessment of Microvascular Function in Patients With Cardiac Amyloidosis
Sponsor: Samsung Medical Center
Summary
The aim of the study is to evaluate coronary flow reserve (CFR), index of microcirculatory resistance (IMR), and proportion of overt microvascular disease, defined as depressed CFR as well as elevated IMR in patients with cardiac amyloidosis. The second objective of this study is to compare results of non-invasive test including serum light chain amount, Doppler echocardiography with 2D strain, and cardiac perfusion MRI. The third object of this study is to evaluate the association between physiologic indices and pathologically measured percent area involvement of interstitium.
Official title: Physiologic Assessment of Microvascular Function in Patients With Cardiac Amyloidosis: Prospective Registry and Pilot Study
Key Details
Gender
All
Age Range
18 Years - 85 Years
Study Type
OBSERVATIONAL
Enrollment
30
Start Date
2016-04-11
Completion Date
2030-12
Last Updated
2025-03-14
Healthy Volunteers
No
Conditions
Locations (1)
Samsung Medical Center
Seoul, South Korea