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Diagnostic and Therapeutic Applications of Microarrays in Lung Transplantation
Sponsor: University of Alberta
Summary
Objective: To evaluate the potential impact of molecular phenotyping of transbronchial biopsies in lung transplant recipients with allograft dysfunction, and the potential for developing a safer endobronchial mucosal biopsy format.
Official title: Multi-Centric Observational Study to Analyze the Diagnostic Molecular Features in the Clinical Setting of Lung Allograft Biopsies
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
700
Start Date
2016-05
Completion Date
2026-12
Last Updated
2025-11-20
Healthy Volunteers
No
Conditions
Interventions
Lung transplant biopsy bites.
In the second phase of the study, two biopsy bites from the same patient will be collected to assess tissue sampling variability.
Locations (11)
St. Joseph's Hospital and Medical Center 350 West Thomas Road, Floor 8HLT
Phoenix, Arizona, United States
University of Maryland School of Medicine
Baltimore, Maryland, United States
Division of Pulmonary and Critical Care, Washington University School of Medicine
St Louis, Missouri, United States
University of Texas at San Antonio
San Antonio, Texas, United States
The Alfred Hospital, Monash University
Melbourne, Australia
Department of Thoracic Surgery, Medical University of Vienna
Vienna, Austria
Alberta Transplant Applied Genomics Centre, University of Alberta
Edmonton, Alberta, Canada
Department of Medicine, University of Alberta
Edmonton, Alberta, Canada
University Health Network, Toronto General Hospital
Toronto, Ontario, Canada
Charles University/Hospital Motol
Prague, Czechia
Thoracic Surgery Transplant Clinic
Szczecin, Poland