Clinical Research Directory

Inclusion Criteria: * Age 18 or over * Septic shock (according to Bone's criteria) within 4 hours of introduction of catecholamines * AKI, characterized by a KDIGO score ≥ 1 * Social security coverage Exclusion Criteria: * AKI requiring emergency RRT (in the critical care physician's opinion). * Anuria * Stage 4-5 chronic kidney failure with a GFR below 30 ml/min. * Rapidly progressing renal disorders (glomerulonephritis, HUS, blockage, etc.) * Obstructive AKI * Probable glomerular damage (nephritic syndrome, nephrotic syndrome, chronic glomerulonephritis) * Pregnancy or breastfeeding * Legal guardianship or lack of social security coverage. * Cardiocirculatory arrest * Life expectancy \<48 hours. * Child C cirrhosis * Prior occurrence of AKI during the current hospital stay * Transplantation * Subject participating in another study with an exclusion period ongoing at the time of the pre-inclusion