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Multi-dose Acetaminophen for Patients Undergoing General Anesthesia
Sponsor: Rutgers, The State University of New Jersey
Summary
Study Objective The aim of the proposed study is to examine the effect of Q4 hour multidose IV acetaminophen on patients' readiness for discharge. In doing so the investigators will also investigate the various factors that could potentially contribute to a patient's readiness for discharge such as overall opioid consumption, time to rescue medication, incidence of postoperative nausea and vomiting, pain scores, and perioperative stress markers and their overall correlation with IV acetaminophen intake.
Official title: A Multi-center, Randomized, Double-blind, Pilot Study on the Effect of Intravenous Multi-dose Acetaminophen on Readiness for Discharge in Patients Undergoing Surgery With General Anesthesia
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
88
Start Date
2017-06-19
Completion Date
2020-12-31
Last Updated
2026-06-08
Healthy Volunteers
No
Conditions
Interventions
Acetaminophen
patients 50kg or more receive1000mg in 100milliliters of normal saline every 4 hours to a maximum dose 4000mg/24 hours. \<50kg receive 12.5mg/kg to a maximum of 75mg/kg/24 hours.
normal saline
100mL of normal saline every 4 hours to a maximum administration of 400mL
Locations (3)
New Jersey Medical School
Newark, New Jersey, United States
University Hospital
Newark, New Jersey, United States
New York Methodist Hospital
Brooklyn, New York, United States