Clinical Research Directory

Inclusion Criteria: * Patient over 18 years * Naive patient to treatment with positive pressure with AHIc \> 15 requiring the establishment of an ASV to a central or combined SAS without any systolic HF (LVEF ≤ 45%) with predominant central SAS. * OR Patient with a predominant obstructive SAS ( ≤ 50% central event ) whose Continuous Positive Airway Pressure treatment (CPAP) does not allow adequate control of the central events: treated for at least 1 month CPAP with a residual central apnea hypopnea index greater than or equal to 10 events per hour (AHI global\> 15, which AHIc ≥ 10) pressure to control obstructive events ( IAHo \<5 ) controlled by polygraphy or polysomnography with a pressure test \<10 cm H2O. * Before inclusion, for patients who have previously been treated with CPAP, a PSG diagnosis will be made after a period of wash-out of CPAP of a 1-week period. * Patient affiliated to the national social security (beneficiary or assignee ). * Patient being aware of the information form and signed informed consent. Exclusion Criteria: * Patients with against -indication for the use of ASV : * History of massive epistaxis. * Diseases related to barotrauma particularly pneumothorax and pneumo- mediastinum. * Suspicions of meningeal gaps or trauma history of the prior stage of the skull base. * Shortness of breath or hypercapnia deemed incompatible by the doctor with the ASV treatment. * Patients with predominant obstructive sleep apnea (OSA) (\> 85% obstructive events ). * Standardized central SAS by the Continuous Positive Airway Pressure * Patients with a diagnosis of systolic heart failure (LVEF ≤45 %) with a predominant central SAS ( \> 50% central events ). * Person deprived of liberty by judicial or administrative decision, person under a legal protection measure (pregnant or lactating women, patients under guardianship) * Lack of signature for the information form and the informed consent form.