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HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease
Sponsor: University College, London
Summary
HDClarity will seek at least 2500 research participants at different stages of Huntington's disease (HD). The primary objective is to collect a high quality CSF sample for evaluation of biomarkers and pathways that will enable the development of novel treatments for HD. The secondary objective is to generate a high quality plasma sample collection matching the CSF collections, which will also be used to evaluate biomarkers and pathways of relevance to HD research and development.
Key Details
Gender
All
Age Range
11 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
2500
Start Date
2017-01-01
Completion Date
Not specified
Last Updated
2025-12-19
Healthy Volunteers
Yes
Conditions
Locations (39)
Cenexel
Englewood, Colorado, United States
Georgetown University
Washington D.C., District of Columbia, United States
John Hopkins University
Baltimore, Maryland, United States
Wake Forest University
Winston-Salem, North Carolina, United States
Vanderbilt University Medical Center
Nashville, Tennessee, United States
University of Texas Health Science Center
Houston, Texas, United States
University of British Columbia, The Centre for Huntingtons Disease
Vancouver, British Columbia, Canada
The Ottawa Hospital
Ottawa, Ontario, Canada
North York General Hospital
Toronto, Ontario, Canada
Centre for Movement Disorders
Toronto, Ontario, Canada
Centre Hospitalier Universitaire d'Angers
Angers, France
Le Centre Hospitalier Universitaire de Bordeaux
Bordeaux, France
University Hospital Ulm
Ulm, Baden-Wurttemberg, Germany
Dresden University
Dresden, Saxony, Germany
St Josef And Elisabeth Hospital
Bochum, Germany
University Hospital of Erlangen
Erlangen, Germany
George Huntington Institute
Münster, Germany
Kbo-Isar-Amper-Klinikum Taufkirchen (Vils)
Taufkirchen, Germany
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Milan, Italy
Lega Italiana Ricera Huntington
Rome, Italy
The University of Auckland
Grafton, Auckland, New Zealand
NZ Brain Research Institute
Christchurch, Canterbury, New Zealand
Institute of Psychiatry and Neurology
Warsaw, Poland
Cruces University Hospital
Bilbao, Biscay, Spain
Hospital de Sant Pau
Barcelona, Spain
Ramón y Cajal Universitary Hospital
Madrid, Spain
Royal Devon & Exeter NHS Foundation Trust
Exeter, Devon, United Kingdom
Glasgow Clinical Research Facility
Glasgow, Scotland, United Kingdom
Birmingham Huntingtons Disease Clinic
Birmingham, West Midlands, United Kingdom
North Bristol NHS Trust
Bristol, United Kingdom
Cambridge University Hospitals NHS Foundation Trust
Cambridge, United Kingdom
Cardiff University
Cardiff, United Kingdom
Fife Health Board - Whyteman's Brae Hospital
Kirkcaldy, United Kingdom
Leeds Teaching Hospital Trust
Leeds, United Kingdom
The Walton Centre NHS Foundation Trust
Liverpool, United Kingdom
University College London Hospitals NHS Foundation Trust
London, United Kingdom
St George's University Of London
London, United Kingdom
Oxford University Hospitals NHS Foundation Trust
Oxford, United Kingdom
University Hospitals Plymouth NHS Trust
Plymouth, United Kingdom