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COMPLETED
NCT02872662

Individual Molecular MRD Monitoring for MDS Patients After Allo-SCT

Sponsor: Nordic MDS Group

View on ClinicalTrials.gov

Summary

This study aims to develop highly sensitive methods for early detection of relapse based on the patients unique mutations. Initially, a mutational screen is being performed. Primers directed against these mutations will be constructed and presence of mutations will be followed in bone marrow and blood frequently after transplantation.

Official title: Individual Molecular Minimal Residual Disease (MRD) Monitoring for Patients With MDS and Mixed MDS/MPN Treated With Allogeneic Stem Cell Transplantation

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

308

Start Date

2016-08

Completion Date

2021-11-22

Last Updated

2026-04-24

Healthy Volunteers

No

Conditions

Locations (8)

Department of Hematology, Aarhus University Hospital

Aarhus, Denmark

Department of Hematology, Rigshospitalet Univsersity Hospital

Copenhagen, Denmark

Department of Medcine, Haukeland University Hospital

Bergen, Norway

Department of Hematology, Rikshospitalet University Hospital

Oslo, Norway

Department of Hematology and Coagulation, Sahlgrenska University hospital

Gothenburg, Sweden

Department of Hematology, Lund University Hospital

Lund, Sweden

Department of Hematology, Karolinska University Hospital

Stockholm, Sweden

Department of Hematology, Akademiska University Hospital

Uppsala, Sweden