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Individual Molecular MRD Monitoring for MDS Patients After Allo-SCT
Sponsor: Nordic MDS Group
Summary
This study aims to develop highly sensitive methods for early detection of relapse based on the patients unique mutations. Initially, a mutational screen is being performed. Primers directed against these mutations will be constructed and presence of mutations will be followed in bone marrow and blood frequently after transplantation.
Official title: Individual Molecular Minimal Residual Disease (MRD) Monitoring for Patients With MDS and Mixed MDS/MPN Treated With Allogeneic Stem Cell Transplantation
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
308
Start Date
2016-08
Completion Date
2021-11-22
Last Updated
2026-04-24
Healthy Volunteers
No
Locations (8)
Department of Hematology, Aarhus University Hospital
Aarhus, Denmark
Department of Hematology, Rigshospitalet Univsersity Hospital
Copenhagen, Denmark
Department of Medcine, Haukeland University Hospital
Bergen, Norway
Department of Hematology, Rikshospitalet University Hospital
Oslo, Norway
Department of Hematology and Coagulation, Sahlgrenska University hospital
Gothenburg, Sweden
Department of Hematology, Lund University Hospital
Lund, Sweden
Department of Hematology, Karolinska University Hospital
Stockholm, Sweden
Department of Hematology, Akademiska University Hospital
Uppsala, Sweden