Circulating Tumor Cells in Patients With Locally Advanced Rectal Cancer

ACTIVE NOT RECRUITING

NCT02874885

Sponsor: M.D. Anderson Cancer Center

Summary

This study looks at the level of circulating tumor elements (cancer cells or DNA pieces floating in the blood) and how it may be related to how the tumor responds to standard treatment in patients with rectal cancer that has spread to nearby tissue or lymph nodes (locally advanced). Researchers will also compare the level and genetic characteristics of circulating tumor elements between individuals with rectal cancer and healthy individuals to understand how they may change over time. Information from this study may help researchers better understand rectal cancer.

Official title: Circulating Tumor Elements in Patients With Rectal Cancer

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

341

Start Date

2013-09-05

Completion Date

2027-04-30

Last Updated

2026-03-11

Healthy Volunteers

Yes

Conditions

Locally Advanced Rectal Adenocarcinoma Metastatic Rectal Adenocarcinoma Rectosigmoid Adenocarcinoma Recurrent Rectal Adenocarcinoma Recurrent Rectosigmoid Carcinoma Stage III Rectal Cancer AJCC v8 Stage IIIA Rectal Cancer AJCC v8 Stage IIIB Rectal Cancer AJCC v8 Stage IIIC Rectal Cancer AJCC v8 Stage IV Rectal Cancer AJCC v8 Stage IVA Rectal Cancer AJCC v8 Stage IVB Rectal Cancer AJCC v8 Stage IVC Rectal Cancer AJCC v8

Interventions

PROCEDURE

Biospecimen Collection

Undergo collection of blood sample

Locations (1)

M D Anderson Cancer Center

Houston, Texas, United States

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