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Dose Optimization in 3D Pulsed Dose Rate Brachytherapy for Patients With Locally Advanced Cervical Cancer
Sponsor: Institut de Cancérologie de Lorraine
Summary
This prospective phase II trial study aims to optimize the increase in dose to the target volume at high risk (85 to 90 Gy over 90% of its volume) and the intermediate target volume (60 Gy to 90 % of its volume) in 3D Pulsed Dose Rate Brachytherapy in treating patients with locally advanced cervical cancer.
Official title: A Prospective Open Label Phase II Study to Optimize the Dose in 3D Pulsed Dose Rate Brachytherapy in Patients With Locally Advanced Cervical Cancer
Key Details
Gender
FEMALE
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
48
Start Date
2011-06-06
Completion Date
2019-07-01
Last Updated
2026-09-01
Healthy Volunteers
No
Conditions
Interventions
External Beam Radiation Therapy
45 Gy pelvis / 25 fr
PDR Brachytherapy
1 puls/hour ; 12 Gy / day
Cisplatin
increase in dose to the target volume at high risk (85 to 90 Gy over 90% of its volume) and the intermediate target volume (60 Gy to 90 % of its volume) in 3D Pulsed Dose Rate Brachytherapy
Locations (9)
CHU de Besançon
Besançon, France
Institut Bergonié
Bordeaux, France
Centre Georges-François Leclerc
Dijon, France
Centre Léon Bérard
Lyon, France
Centre Val d'Aurelle
Montpellier, France
Centre Paul Strauss
Strasbourg, France
Centre Claudius Regaud
Toulouse, France
CHRU Tours - Hôpital Bretonneau
Tours, France
Institut de Cancérologie de Lorraine
Vandœuvre-lès-Nancy, France