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RECRUITING
NCT02902198
NA

Taste Physiology in Obese Volunteers Before and After Bariatric Surgery

Sponsor: University Hospital, Basel, Switzerland

View on ClinicalTrials.gov

Summary

The objective is to investigate neuro-anatomical correlates of gastrointestinal taste stimulation by means of functional MRI before and after bariatric surgery. Intragastric administration of glucose, monosodium glutamate, chloroquine and placebo is followed by functional brain MRI in obese humans before and 3 months after surgery.

Key Details

Gender

All

Age Range

18 Years - 55 Years

Study Type

INTERVENTIONAL

Enrollment

16

Start Date

2014-12

Completion Date

2027-12

Last Updated

2025-04-03

Healthy Volunteers

No

Conditions

Interventions

DIETARY_SUPPLEMENT

Placebo

Tap water 200ml

DIETARY_SUPPLEMENT

Glucose

25g Glucose in 200ml tap water

DIETARY_SUPPLEMENT

Monosodium glutamate

1g monosodium glutamate in 200ml tap water

DIETARY_SUPPLEMENT

Quinine

17mg quinine in 200ml tap water

Locations (1)

University Hopital Basel

Basel, Switzerland