Clinical Research Directory

Inclusion Criteria are: For HIV-1-infected subjects group : * Age at least 18-year old * HIV-1 infection * Receiving continuous cART for ≥ 12 months, started during the chronic phase * Plasma viral load ≤50 copies/mL for ≥ 6 months (one blip ≤200 copies/mL authorized) * Blood CD4+ T cells count ≥ 350 cells/mm3 * Indication for upper and/or lower digestive endoscopy * Patient enrolled in or a beneficiary of a Social Security programme (State Medical Aid or AME is not a Social Security programme) * Written informed consent. For uninfected control group : * Age at least 18-year old * Indication for upper and/or lower digestive endoscopy * Patient enrolled in or a beneficiary of a Social Security programme (State Medical Aid or AME is not a Social Security programme) * Written informed consent Exclusion Criteria are: For HIV-1-infected subject group : * HIV-2 infection * Inflammatory bowel diseases (Crohn's disease, ulcerative colitis) ; coeliac disease * Platelets count \<50 G/L or abnormal hemostasis tests * Decompensated cirrhosis * Past or current lymphoma * Involvement in an HIV-1 immunotherapeutic vaccine study * Pregnant or breastfeeding women * Subjects participating in a study excluding participating in another study * Vulnerability, such as an age under 18, tutorship, trusteeship, or subjects deprived of liberty by a legal or administrative decision. For uninfected control group : * HIV-1 and 2 infection * Inflammatory bowel diseases (Crohn's disease, ulcerative colitis) ; coeliac disease * Platelets count \<50 G/L or abnormal hemostasis tests * Decompensated cirrhosis * Past or current lymphoma * Pregnant or breastfeeding women * Subjects participating in a study excluding participating in another study * Vulnerability, such as an age under 18, tutorship, trusteeship, or subjects deprived of liberty by a legal or administrative decision