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ACTIVE NOT RECRUITING
NCT02955940
PHASE2

An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib

Sponsor: Incyte Corporation

View on ClinicalTrials.gov

Summary

The purpose of this study is to provide continued supply of ruxolitinib alone, ruxolitinib plus background cancer therapy, or background cancer therapy alone to subjects from an Incyte-sponsored study of ruxolitinib that has reached its study objectives or has been terminated. This study will also provide another mechanism for reporting adverse events related to study drug safety.

Official title: An Open-Label, Multicenter, Rollover Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

10

Start Date

2016-11-30

Completion Date

2027-09-30

Last Updated

2025-12-17

Healthy Volunteers

No

Interventions

DRUG

Ruxolitinib

5 mg BID

DRUG

Capecitabine

Capecitabine at the same dose provided in the parent study at the time of the rollover.

DRUG

Regorafenib

Regorafenib at the same dose provided in the parent study at the time of the rollover.

Locations (9)

UCLA Healthcare Hematology-Oncology

Santa Monica, California, United States

University of Louisville

Louisville, Kentucky, United States

New York Oncology Hematology Pc.

Clifton Park, New York, United States

Tennessee Oncology

Nashville, Tennessee, United States

University of Texas M. D. Anderson Cancer Center

Houston, Texas, United States

Renovatio Clinical Consultants Llc

The Woodlands, Texas, United States

Sp Zoz Szpital Uniwersytecki W Krakowie Oddzial Kliniczny Hematologii

Krakow, Poland

Samodzielny Publiczny Szpital Kliniczny

Lublin, Poland

Instytut Hematologii I Transfuzjologii

Warsaw, Poland