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An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib
Sponsor: Incyte Corporation
Summary
The purpose of this study is to provide continued supply of ruxolitinib alone, ruxolitinib plus background cancer therapy, or background cancer therapy alone to subjects from an Incyte-sponsored study of ruxolitinib that has reached its study objectives or has been terminated. This study will also provide another mechanism for reporting adverse events related to study drug safety.
Official title: An Open-Label, Multicenter, Rollover Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
10
Start Date
2016-11-30
Completion Date
2027-09-30
Last Updated
2025-12-17
Healthy Volunteers
No
Interventions
Ruxolitinib
5 mg BID
Capecitabine
Capecitabine at the same dose provided in the parent study at the time of the rollover.
Regorafenib
Regorafenib at the same dose provided in the parent study at the time of the rollover.
Locations (9)
UCLA Healthcare Hematology-Oncology
Santa Monica, California, United States
University of Louisville
Louisville, Kentucky, United States
New York Oncology Hematology Pc.
Clifton Park, New York, United States
Tennessee Oncology
Nashville, Tennessee, United States
University of Texas M. D. Anderson Cancer Center
Houston, Texas, United States
Renovatio Clinical Consultants Llc
The Woodlands, Texas, United States
Sp Zoz Szpital Uniwersytecki W Krakowie Oddzial Kliniczny Hematologii
Krakow, Poland
Samodzielny Publiczny Szpital Kliniczny
Lublin, Poland
Instytut Hematologii I Transfuzjologii
Warsaw, Poland