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Surrogate Markers of Response to New Therapies in Cystic Fibrosis Patients
Sponsor: Hôpital Necker-Enfants Malades
Summary
The purpose of this study is to determine which biological marker, or association of biological markers, best predict clinical response of cystic fibrosis patients to CFTR modulators.
Official title: Personalized Therapy of Cystic Fibrosis: Set-up of Response Markers
Key Details
Gender
All
Age Range
Any - Any
Study Type
INTERVENTIONAL
Enrollment
75
Start Date
2016-05
Completion Date
2026-10
Last Updated
2024-03-12
Healthy Volunteers
No
Conditions
Interventions
Nasal swab; rectal biopsy.
Nasal epithelial cells will be obtained by nasal swabs from patients of the three arms; intestinal epithelial cells will be obtained, by rectal biopsy, only from patients treated by CFTR modulators.
Locations (1)
Necker Hospital
Paris, France