Clinical Research Directory

Inclusion criteria 1. Male and female Chinese patients aged ≥18 to ≤60 years 2. Patients with a first episode of optic neuritis in the eye of interest 3. First symptoms of optic neuritis ≤28 days prior to the first administration of investigational product 4. Best corrected visual acuity in the eye of interest ≤0.8 Exclusion criteria 1. Pre-existing multiple sclerosis MS or NMO 2. Refractive media opacity 3. Hyperopia \>5 diopters, myopia \<-5 diopters, or astigmatism \>3 diopters 4. Active tuberculosis, hepatitis, renal insufficiency, uncontrolled hypertension, diabetes mellitus, infection with HIV or syphilis, or any other conditions potentially interfering treatment trial 5. Other autoimmune diseases (systemic lupus erythematosus, rheumatoid arthritis, etc) 6. Existing other retina or optic nerve diseases 7. Pregnant or females who plan to be pregnant during study