Clinical Research Directory

Cross-sectional (parent) study: Inclusion Criteria: Patients ages \>18 years of age referred for right heart catheterization for further evaluation of known PVD or to be at risk for PVD due to established cardiac disease or pulmonary disease * Able to perform complete diagnostic testing listed subsequently (cardiac catheterization, echo, exercise test, PFT's, ECG, chest CT, quality of life questionnaires, ventilation/perfusion scan, cardiac MRI, body composition bioimpedance, and sleep study) * Subject signs informed consent to perform required testing for the protocol Exclusion Criteria: Dialysis dependent renal function; In the clinician's opinion, too ill to perform the protocol testing; Pregnant or nursing Longitudinal study: Inclusion Criteria: * Any PH, comparators or control participant previously enrolled in the parent PVDOMICS protocol with a minimum of six months post-enrollment * Dialysis dependent renal function since the parent study acceptable Exclusion Criteria: Participant Level 1 (clinic visit): * Transplant other than heart or lung * In the clinician's opinion, too ill to perform L-PVDOMICS testing even if limited testing. * Participants who withdrew from the parent PVDOMICS study * Pregnant or nursing * Concurrent participation in any investigational drug study or other clinical trial Participant Level 2 (telephone visit): * Transplant other than heart or lung * Participants who withdrew from the parent PVDOMICS study Participant Level 3 (medical chart review): \- Participants who withdrew from the parent PVDOMICS study