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Exercise Effect on Chemotherapy-Induced Neuropathic Pain
Sponsor: Baltimore VA Medical Center
Summary
Chemotherapy-induced peripheral neuropathy (CIPN) continues to be a serious healthcare concern. It is painful, persistent, resistant to conventional pain therapies, and results in long-term suffering and decreased quality of life for many cancer survivors. The role of exercise to decrease CIPN-related neuropathic pain (CIPN-NP) will be investigated, with the goal of identifying the mechanisms associated with this therapeutic approach to manage CIPN-NP.
Official title: Exercise Effect on Chemotherapy-Induced Neuropathic Pain, Peripheral Nerve Fibers
Key Details
Gender
All
Age Range
21 Years - 70 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2018-03-01
Completion Date
2025-12
Last Updated
2024-08-06
Healthy Volunteers
No
Interventions
aerobic exercise intervention
Exercise physiologist supervised walking or running on the treadmill 3 times weekly for 12 weeks.
control group
weekly contact by study staff with survivorship information offered not related to neuropathy.
resistive training
Exercise physiologist supervised upper and lower extremity resistive training 3 times weekly for 12 weeks
Locations (1)
Baltimore VA Medical Center
Baltimore, Maryland, United States