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Antimicrobial Prophylaxis for Skin Colonization With Propionibacterium Acnes in Primary Open Shoulder Surgery
Sponsor: Université de Montréal
Summary
INESS Antibiotic Prophylaxis in Orthopedic Guide recommends the use of Cefazolin at induction for all orthopaedic procedure with implantation of internal fixation device. With the increasing rate of identified P. acnes shoulder surgery infection despite the use of recommended skin preparation and preoperative prophylactic antibiotics, a question arises; Is Cefazolin the most effective prophylactic antibiotic for shoulder surgery? The objective of this study is to determine if Ceftriaxone is superior to Cefazolin as a prophylactic antibiotic for skin colonization with P. acnes in primary shoulder surgery
Official title: Antimicrobial Prophylaxis for Skin Colonization With Propionibacterium Acnes in Primary Open Shoulder Surgery: A Double Blinded Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
88
Start Date
2016-12
Completion Date
2026-12
Last Updated
2025-08-08
Healthy Volunteers
No
Conditions
Interventions
Cefazolin
Antibiotic that will be give before a Trauma or elective open shoulder surgery
Ceftriaxone
Antibiotic that will be give before a Trauma or elective open shoulder surgery
Locations (1)
Hôpital du Sacré-Cœur de Montréal
Montreal, Quebec, Canada