Clinical Research Directory

Patient eligibility criteria are designed to limit enrollment otherwise healthy individuals who are scheduled for standard-of-care nasal endoscopy in the clinic or sinus/skull base surgery. Inclusion criteria: * Age \> 18 years * Able to give consent * A diagnosis of CRS, as determined by the Sinus and Allergy Health Partnership criteria * Has cultured out at least one gram negative bacteria (e.g. Pseudomonas aeruginosa, Escherichia coli, Stenotrophomonas maltophila) within the previous month * Is scheduled for either routine endoscopic surgery or has previously undergone endoscopic surgery and presents to clinic for routine endoscopic evaluation Exclusion criteria: * Age \< 18 years * Unable to give consent * Active diagnosis of cancer, autoimmune disease, or any know immunodeficiency * Women who are pregnant or breastfeeding