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Collection and Measurement of Biomarkers in Prostate Cancer Radiotherapy Patients
Sponsor: University of Miami
Summary
The purpose of this research study is to learn about: 1) How standard radiation treatment to prostate (primary radiotherapy) or the pelvis after prostatectomy (postoperative radiotherapy) may cause changes in MRI and PET imaging traits that might be used in the future to predict response. 2) Comparison of such MRI and PET imaging traits with the number of circulating tumor cells (CTCs) present in the blood prior to treatment and the changes in these counts after treatment. 3) How MRI and PET imaging characteristics and changes are related to the expression of genes in the cancer tissue obtained before treatment from prostate biopsy or a prior prostatectomy before treatment. 4) How the response of prostate cancer treatment relates to the imaging and CTC changes.
Official title: Collection and Measurement of Blood and Imaging Biomarkers in Patients Undergoing Standard Primary and Postoperative Radiotherapy for Prostatic Neoplasms - The Miami CoMBINe Trial
Key Details
Gender
MALE
Age Range
30 Years - Any
Study Type
OBSERVATIONAL
Enrollment
144
Start Date
2016-06-24
Completion Date
2032-06-30
Last Updated
2026-03-04
Healthy Volunteers
No
Conditions
Locations (1)
University of Miami
Miami, Florida, United States