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ACTIVE NOT RECRUITING
NCT03018418
PHASE2

Proton Therapy in Reducing Toxicity in Anal Cancer

Sponsor: Jordan Kharofa

View on ClinicalTrials.gov

Summary

The purpose of this research study is to determine whether the amount of radiation given to the normal areas around the anal cancer can be reduced by using Proton Therapy while reducing the side effects that are seen with standard therapy.

Official title: A Prospective Pilot Study to Evaluate the Feasibility of Intensity Modulated Proton Therapy in Reducing Toxicity in Anal Cancer

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

14

Start Date

2017-01-04

Completion Date

2025-07-01

Last Updated

2024-09-19

Healthy Volunteers

No

Conditions

Interventions

RADIATION

Proton therapy

Primary target volume 50.4-54 CGE in 28-30 fractions; Nodal volumes 42-54 CGE in 28-30 fractions

DRUG

Chemotherapy

5FU 1000 mg/m2/day as 96 hour infusion days 1-5 and 29-33; Mitomycin 10mg/m2 days 1 and 29

Locations (1)

UC Health

Cincinnati, Ohio, United States