Clinical Research Directory

Inclusion Criteria: * 22 years of age or older * Able to undergo the informed consent/assent process * Stable, motor-complete paraplegia * Discrete spinal cord injury between C6 and T10 * ASIA A or B Spinal Cord Injury Classification * Medically stable in the judgement of the principal investigator * Intact segmental reflexes below the lesion of injury * Greater than 1 year since initial injury and at least 6 months from any required spinal instrumentation * Willing to attend all scheduled appointments Exclusion Criteria: * Diseases and conditions that would increase the morbidity and mortality of spinal cord injury surgery (e.g. cardiopulmonary issues) * Inability to withhold antiplatelet/anticoagulation agents perioperatively * Significant dysautonomia that would prohibit rehabilitation or assisted standing or any history of CVA or MI associated with autonomic dysreflexia. A single tilt table test with syncope, presyncope, or SBP \< 50 or \>200. * Other conditions that would make the subject unable to participate in testing/rehabilitation in the judgement of the principal investigator * Current and anticipated need for opioid pain medications or pain that would prevent full participation in the rehabilitation program in the judgement of the principal investigator * Clinically significant mental illness in the judgement of the principal investigator * Botulinum toxin injections in the previous 6 months * Volitional movements present during EMG testing in bilateral lower extremities * Unhealed spinal fracture * Presence of significant contracture * Presence of pressure ulcers * Recurrent urinary tract infection refractory to antibiotics * Current Pregnancy