Clinical Research Directory

Inclusion Criteria: * All patients 3 months to 18 years of age attending the pediatric ED and diagnosed with a non-severe pneumonia, will be considered for enrolment. More precisely, the following inclusion criteria will be required: 1. Presence of respiratory symptoms (cough and/or dyspnea) 2. Presence of signs of pneumonia (tachypnea, abnormal breath sounds, crackles) 3. Presence of fever 4. Positive chest radiography as interpreted by the treating physician Exclusion Criteria: * Any danger signs associated with pneumonia (severe indrawing, shock or severe dehydration, empyema, important pleural effusion, pulmonary abcess or pneumatocoele) * History of anaphylactic or allergic reaction to penicillin or amoxicillin according to the treating physician. * History of a serious nonimmunoglobulin E-mediated reactions (eg, Stevens-Johnson syndrome or toxic epidermal necrolysis) attributed to amoxicilin. * Caregiver unable to provide consent (language barrier or lack of caregiver presence) * Underlying unstable chronic illness (ie. cystic fibrosis, immune suppression, active tuberculosis, bronchiectasis or active pulmonary malignancies) * Persistent/chronic pneumonia syndromes (with symptoms for \>2 weeks), suspected by the physician to be caused by atypical pathogens, hospital- acquired pneumonia (been hospitalized within 2 weeks prior to enrolment), aspiration pneumonia or recurrent pneumonias. * Any history of receiving amoxicillin within the past month * Need hospitalisation for any other reasons (ie. persistent vomiting, severe life-threatening infection such as septicaemia or meningitis requiring intravenous antimicrobial agents) * Previous participation in study