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Patient-Centered NeuroRehabilitation (PCN)
Sponsor: University of Michigan
Summary
As individuals grow older, a number of factors can reduce our cognitive (or thinking) abilities such as "normal" aging, neurodegenerative diseases, and cardiovascular disease. This study will evaluate whether cognitive rehabilitation and transcranial electrical stimulation (TES) can improve cognitive abilities. Cognitive rehabilitation refers to methods that are used to improve tasks people have trouble doing in everyday life. Transcranial electrical stimulation uses small amounts of electricity to try to alter brain functioning. These approaches may help improve cognitive abilities like attention, learning, memory, finding words, and problem solving as well as everyday functioning. The goal of this study is to identify how to best use these methods, either alone or in combination.
Official title: Patient-Centered NeuroRehabilitation
Key Details
Gender
All
Age Range
50 Years - Any
Study Type
INTERVENTIONAL
Enrollment
500
Start Date
2016-06
Completion Date
2027-11
Last Updated
2026-01-14
Healthy Volunteers
Yes
Conditions
Interventions
Active tDCS
Participants will receive active tDCS at up to 4mA per electrode for up to 40 minutes for up to 260 sessions.
Sham tDCS
Participants will receive sham tDCS for up to 260 sessions
Cognitively based intervention
Participants may receive a cognitively based intervention that targets the particular cognitive and/or functional abilities of interest. This includes methods of cognitive training, cognitive remediation, and cognitive rehabilitation for up to 260 sessions
Active tACS
Participants will receive active transcranial alternating current stimulation at up to 4mA per electrode for up to 40 minutes for up to 260 sessions
Sham tACS
Participants will receive sham transcranial alternating current stimulation for up to 260 sessions
Active tRNS
Participants will receive active transcranial random noise stimulation at up to 4mA per electrode for up to 40 minutes for up to 260 sessions
Sham tRNS
Participants will receive sham transcranial random noise stimulation for up to 260 sessions
Locations (1)
University of Michigan - Department of Psychiatry
Ann Arbor, Michigan, United States