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Corneal Collagen Crosslinking to Increase the Resistance of the Support Graft of the KPro Type I Against Corneal Melting
Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
Summary
The purpose of this study is to demonstrate the safety and efficacy of the corneal collagen crosslinking with riboflavin and ultraviolet A in aim to increase the resistance of the graft used as a support for the Boston keratoprosthesis (KPro) type I against corneal melting (keratolysis or sterile necrosis).
Official title: Corneal Collagen Crosslinking to Increase the Resistance of the Graft Used as a Support for the Boston Keratoprosthesis Type I Against Corneal Melting
Key Details
Gender
All
Age Range
18 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
40
Start Date
2017-01-04
Completion Date
2025-01
Last Updated
2024-04-19
Healthy Volunteers
No
Interventions
Crosslinking with riboflavin of the corneal graft-support
Corneal graft support for the KPro will be crosslinked and used with the standard surgical technique
De-epithelisation of the corneal graft support with instillation of riboflavin
Corneal graft-support will be de-epithelialized and soaked with riboflavin and then used with the standard surgical technique
Locations (1)
Centre Hospitalier de l'Université de Montréal
Montreal, Quebec, Canada