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RECRUITING
NCT03047369

The Myelin Disorders Biorepository Project

Sponsor: Children's Hospital of Philadelphia

View on ClinicalTrials.gov

Summary

The Myelin Disorders Biorepository Project (MDBP) seeks to collect and analyze clinical data and biological samples from leukodystrophy patients worldwide to support ongoing and future research projects. The MDBP is one of the world's largest leukodystrophy biorepositories, having enrolled nearly 2,000 affected individuals since it was launched over a decade ago. Researchers working in the biorepository hope to use these materials to uncover new genetic etiologies for various leukodystrophies, develop biomarkers for use in future clinical trials, and better understand the natural history of these disorders. The knowledge gained from these efforts may help improve the diagnostic tools and treatment options available to patients in the future.

Official title: The Myelin Disorders Biorepository Project and Global Leukodystrophy Initiative Clinical Trials Network

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

12000

Start Date

2016-12-08

Completion Date

2030-12-08

Last Updated

2025-10-23

Healthy Volunteers

No

Conditions

Locations (23)

Children's Hospital of Los Angeles

Los Angeles, California, United States

Children's Hospital of Orange County

Orange, California, United States

Stanford University (Lucile Packard Children's Hospital)

Palo Alto, California, United States

University of California, Davis (UC Davis Health)

Sacramento, California, United States

University of California, San Diego (Rady Children's Hospital)

San Diego, California, United States

UCSF Benioff Children's Hospital

San Francisco, California, United States

Children's National Medical Center

Washington D.C., District of Columbia, United States

Emory University (Children's Healthcare of Atlanta)

Atlanta, Georgia, United States

Ann & Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, United States

Kennedy Krieger Institute

Baltimore, Maryland, United States

Massachusetts General Hospital (MGH)

Boston, Massachusetts, United States

University of Minnesota

Minneapolis, Minnesota, United States

Mayo Clinic

Rochester, Minnesota, United States

Atrium Health Wake Forest Baptist

Winston-Salem, North Carolina, United States

Akron Children's Hospital

Akron, Ohio, United States

Nationwide Children's Hospital

Columbus, Ohio, United States

The Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States

University of Pennsylvania

Philadelphia, Pennsylvania, United States

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States

Baylor College of Medicine (Texas Children's Hospital)

Houston, Texas, United States

UT Health Houston

Houston, Texas, United States

University of Utah (Primary Children's Hospital)

Salt Lake City, Utah, United States

Seattle Children's Hospital

Seattle, Washington, United States