Clinical Research Directory

Inclusion Criteria: 1. Subject is able to provide written informed consent to participate in the study before completing any study-related procedures 2. Subject is male or female aged 18-75 years, inclusive at time of consent. 3. Subject has a documented diagnosis of achalasia based on high resolution manometry and endoscopy report. 4. Subject has been or will be scheduled to undergo either EGD with pneumatic dilation or surgical myotomy as routine care for treatment of achalasia. 5. Subject is willing and has an understanding and ability to fully comply with study procedures and restrictions defined in this protocol. Exclusion Criteria: 1. Subject has any condition or abnormality, current or past that, in the opinion of the principal investigator, would compromise the safety of the subject or interfere with or complicate the assessment of signs or symptoms of achalasia. Such conditions may include psychiatric problems; neurologic deficits or disease; developmental delay; lung transplant; or previous gastroesophageal surgery. 2. Subject has had previous pneumatic dilation of treatment of achalasia. 3. Subject has had botulinum toxin (botox) injection for treatment of achalasia. 4. Subject has a history or high risk of noncompliance with treatment or regular clinic visits.