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Effect of Tranexamic Acid (TXA) on Reduction of Postoperative Blood Transfusion
Sponsor: Gregory M Georgiadis MD
Summary
Tranexamic Acid (TXA) is an antifibrolytic medication used in total hip and knee arthroplasty to reduce the need for intraoperative and postoperative blood transfusions. Limited research is available on its use in hip fracture patients. We hypothesize that the use of TXA preoperatively, perioperatively, and postoperatively will decrease blood loss and need for blood transfusion postoperatively.
Official title: Evaluating the Effect of Tranexamic Acid (TXA) on Reduction of Postoperative Blood Transfusion in Hip Fracture Patients
Key Details
Gender
All
Age Range
60 Years - Any
Study Type
INTERVENTIONAL
Enrollment
200
Start Date
2017-08-30
Completion Date
2026-09-01
Last Updated
2025-08-07
Healthy Volunteers
No
Conditions
Interventions
Tranexamic Acid (TXA)
Tranexamic acid is an antifibrinolytic used to control bleeding
Saline solution
Saline solution is used as the placebo comparator
Locations (1)
ProMedica Toledo Hospital
Toledo, Ohio, United States