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The Role of Large Artery Plaque Imaging Features in Predicting Inflammation and Cognition
Sponsor: Scott Mcnally
Summary
The invesigators propose a clinical study on patients undergoing carotid surgery (endarterectomy). The invesigators will determine carotid artery imaging features associated with (1) vessel wall inflammation, (2) downstream brain inflammation, and (3) cognitive benefit from surgery. This project will uncover links between inflamed carotid plaque and downstream brain inflammation. The invesigators will also determine carotid plaque imaging features predicting cognitive benefit from carotid surgery.
Official title: Amyloid Deposition and Preexisting Vulnerable Carotid Plaque Features Predicting Cognitive Improvement After Surgery
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
45
Start Date
2017-02-17
Completion Date
2030-09-10
Last Updated
2026-05-13
Healthy Volunteers
No
Interventions
Imaging with flutemetamol F 18 PET/CT
All subjects will undergo diagnostic imaging as the intervention. This imaging will be with flutemetamol F 18 PET/CT
Locations (2)
University of Utah
Salt Lake City, Utah, United States
George E. Wahlen Department of Veterans Affairs Medical Center
Salt Lake City, Utah, United States