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Peri-implantitis - Reconstructive Surgical Therapy
Sponsor: Göteborg University
Summary
The project will evaluate the potential benefit of the use of bone replacement graft as an adjunct to surgical therapy of peri-implantitis. The project will be conducted as a two-armed randomized controlled clinical trial of 5-year duration in 7 clinical centers. 140 systemically healthy patients diagnosed with peri-implantitis will randomly assigned to be treated with or without bone replacement graft. Outcome measures include assessments of inflammation, probing depth, recession, radiological parameters and PROMs.
Official title: Reconstructive Surgical Therapy of Peri-implantitis-related Osseous Defects. A Multicenter Randomized Controlled Clinical Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
140
Start Date
2017-04-01
Completion Date
2026-03-14
Last Updated
2024-10-15
Healthy Volunteers
No
Conditions
Interventions
Open flap debridement
Open flap debridement using saline as irrigation
Bone replacement graft
Open flap debridement using saline as irrigation including a grafting procedure withBio-Oss Collagen®.
Locations (1)
Department of Periodontology, Institute of Odontology
Gothenburg, Sweden