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Retrospective Study of Viral Reactivation Across All Bone Marrow Transplant Protocols Since 2010
Sponsor: National Cancer Institute (NCI)
Summary
Background: Some blood and immune disorders can be helped with HSCT. This is allogeneic hematopoietic stem cell transplantation. The person who gets the stem cells has their immune system suppressed. This is done to help prevent their body from rejecting the transplant. During this time, the person is at a high risk to get viral infections. Researchers want to study the records of people who had transplants a few years ago. They want to look at how often certain viral complications happened. Objective: To study how often certain viral complications occurred after HSCT and what risks factors were involved. Eligibility: Records will be reviewed. No participants will be contacted. Design: Researchers will review medical records from the NIH Clinical Center. The records will be from people who had HSCT between 2010 and 2015 when they were between 4 and 85 years old. They already gave consent for their data to be studied. Data collected will include: Vital statistics like age and sex Viral status of the recipient and donor Reason for transplant Transplant details How the immune system recovered after transplant If the recipient got graft versus host disease Any infections Overall survival ...
Key Details
Gender
All
Age Range
4 Years - 85 Years
Study Type
OBSERVATIONAL
Enrollment
730
Start Date
2017-04-13
Completion Date
2020-02-18
Last Updated
2026-04-20
Healthy Volunteers
No
Conditions
Locations (1)
National Cancer Institute (NCI)
Bethesda, Maryland, United States