Clinical Research Directory

Inclusion Criteria: 1. smoke ≥5 cigarettes per day for the past year; 2. no quit attempt in the prior 3 months and no plan to quit in the next 3 months; 3. read, write, and speak in English; 4. report at least minimal interest in switching to an alternative product (\> "not at all" on a Likert scale); 5. never purchased or regularly used a tank system, mechanical mod, or advanced personal vaporizer EC, though previous use of cig-a-like devices will be allowed but not in the last 3 months; 6. plan to live in the local area for next year; and 7. have reliable means of transport. - Exclusion Criteria: 1. \<18 years old; 2. unstable or significant medical condition such as respiratory, kidney, or liver disease that could potentially affect biomarker data; 3. unstable or significant psychiatric conditions (past and stable conditions will be allowed); 4. history of cardiac event or distress within the past 3 months; and 5. currently pregnant, planning to become pregnant, or breastfeeding (n.b: pregnancy status will continue to be evaluated throughout the study at each visit). \-