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The K-Map Study, Global Prevalence of KC
Sponsor: University Hospital, Geneva
Summary
Keratoconus is a ocular disease classified under ectatic diseases which often results in bilateral and asymmetrical corneal distortion. It usually affects patients at young age and can cause severe visual loss. The overall goal of this study is to assess the prevalence of keratoconus (KC) in children and adolescents in various regions of the world based on modern tomographic imaging methods, and to verify whether the occurrence rates reported from literature should be corrected. Our hypothesis is that the prevalence of the disease is much higher than that traditionally reported. At each site, corneal tomography examinations (Pentacam) will be performed bilaterally in children and adolescents, who are not ill or with any ophthalmological symptom. The population to be studied will be composed of children and adolescents on medical visits for non-ophthalmologic reasons, aged between 6 and 20 years. Multiple cities, from different continents (North America, South America, Asia and Europe) will participate.
Key Details
Gender
All
Age Range
6 Years - 23 Years
Study Type
OBSERVATIONAL
Enrollment
20000
Start Date
2015-12-28
Completion Date
2030-02-01
Last Updated
2025-08-11
Healthy Volunteers
Yes
Conditions
Interventions
Rotating Scheimpflug camera (Pentacam HR)
One visit to Ophthalmology Department is required from participant. Parents or legal guardians must attend with their child. The interview and test during visit take approximately 15 minutes. Interview includes filling out a questionnaire about risk factors of the disease and double check on understanding the consent form. The child will sit in front of the instrument (Pentacam HR Scheimpflug imaging system). The rotational measuring procedure generates Scheimpflug images in three dimensions. The images taken during the examination are digitalized, and all image data are transferred to the computer. It calculates a 3D virtual model of the anterior eye segment, from which all additional information is derived.
Locations (12)
USC Roski Eye Institute
Los Angeles, California, United States
Eye Hospital of Wenzhou Medical College
Wenzhou, China
Zagreb, Croatia
Alexandria, Egypt
Homburg, Germany
Isfahan, Iran
Amman, Jordan
Monterrey, Mexico
Lima, Peru
Ufa Eye Research Intitute
Ufa, Russia
King Saud University
Riyadh, Saudi Arabia
Bukhara, Uzbekistan